Why support RSRT UK

Rett Syndrome research has advantages not available to many other neurological disorders:
  • an identified gene
  • excellent animal models
  • links to a variety of neuropsychiatric disorders
  • an elite group of committed researchers
  • spectacular science which recently culminated with the prospect of reversibility

Rett Syndrome Research Trust UK also has unique advantages:

  • One focus: research
  • Financially lean and efficient
  • Designed to be agile and responsive to changes in the field
  • Collaboration with RSRT whose founders and advisors have been largely responsible for major advances in the field in the last decade
  • Driven entirely by families whose only interest is in accelerating treatment

 

Once, Rett research was focused on diagnosis and prevention but the reversal experiments of 2007 have changed everything. Now, girls and women with Rett Syndrome can afford the possibility of hoping that one day the myriad of symptoms they wrestle daily, will disappear, one by one.

'Like many other people, we expected that giving MECP2 to mice that were already sick would not work. The idea that you could put back an essential component after the damage to the brain is done and recover an apparently normal mouse seemed far-fetched, as nerve cells that developed in the absence of a key component were assumed to be irrevocably damaged. The results are gratifyingly clear, though, and must give hope to those who are affected by this distressing disorder.'

Adrian P. Bird, Ph.D.
University of Edinburgh

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