
Rett Syndrome Research Trust UK also has unique advantages:
Once, Rett research was focused on diagnosis and prevention but the reversal experiments of 2007 have changed everything. Now, girls and women with Rett Syndrome can afford the possibility of hoping that one day the myriad of symptoms they wrestle daily, will disappear, one by one.
'Like many other people, we expected that giving MECP2 to mice that were already sick would not work. The idea that you could put back an essential component after the damage to the brain is done and recover an apparently normal mouse seemed far-fetched, as nerve cells that developed in the absence of a key component were assumed to be irrevocably damaged. The results are gratifyingly clear, though, and must give hope to those who are affected by this distressing disorder.'
Adrian P. Bird, Ph.D.
University of Edinburgh
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