CPMRS interventions are based on a holistic multi-modal approach. Recommendations regarding intervention are made and pharmacological treatment is initiated as part of Shared Care Protocol with local services. The individual is reviewed by telephone during the initial titration phase and during any medication changes. Once medication is stabilised, they are reviewed within the follow up clinic and co-worked with local services, with a view to maintaining stabilisation. In addition, consultation and supervision is offered to local services to help them to modify interventions to take into account the individual’s complex neuropsychiatric and neurodevelopmental difficulties. Patient data will be used for research to improve clinical care.