MECP2 Duplication Syndrome is reversible

In 2007 Adrian Bird rocked the Rett world with the unexpected news that Rett symptoms in mice were dramatically reversible.

With the advent of a mouse model for the MECP2 Duplication Syndrome a big question loomed – would the duplication disorder...

Research made easy: Sarizotan

What is Sarizotan and how might it help people with Rett Syndrome?

Sarizotan is a drug which has been shown to significantly improve some aspects of the breathing problem in Rett mice.

The drug is now in development by a pharmaceutical company...

Research made easy: About PTP1B

By Rachael Bloom Stevenson

What is PTPB1?

PTP1B is an enzyme which can reduce signalling of two important hormones in the human body, insulin and leptin.

Insulin is a hormone made by the pancreas that allows your body to use sugar (glucose) from...

Latest update from King’s College London

Pictured above, Dr Paramala Santosh, leading the clinical research team at King's College London and research assistant, Federico Fiori, with Rachael Bloom, Executive Director & John Sharpe, Chairman of Reverse Rett

Last year, Reverse Rett provided...

Research made easy: Ketamine Clinical Trial

by Rachael Bloom

Ketamine? Isn’t that a tranquiliser?

Ketamine is a sedative which is most often used as an anaesthetic in operations. However, at much lower doses it has been shown to significantly improve symptoms in disorders such as major...

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